Effect of autogenous tooth bone graft with membrane on Class II furcation defects in dogs: A histologic and histomorphometric study
양건일, 조아영, 양진용, 신홍인, 이원표, 김병옥, 유상준,
소속 상세정보
양건일 ( Yang Keon-Il ) - Chosun University School of Dentistry Department of Periodontology
조아영 ( Cho Ah-Young ) - Chosun University School of Dentistry Department of Periodontology
양진용 ( Yang Jin-Young ) - Chosun University School of Dentistry Department of Periodontology
신홍인 ( Shin Hong-In ) - Kyungpook National University School of Dentistry Department of Oral Pathology
이원표 ( Lee Won-Pyo ) - Chosun University School of Dentistry Department of Periodontology
김병옥 ( Kim Byung-Ock ) - Chosun University School of Dentistry Department of Periodontology
유상준 ( Yu Sang-Joun ) - Chosun University School of Dentistry Department of Periodontology
Abstract
The study evaluated the efficacy of combining autogenous tooth bone grafts with membranes in surgically created class II furcation defects. Thirty teeth of 10 dogs were assessed. Furcation defects (5 × 4 × 3 mm3) were created in the lower third and fourth premolars. Defects in the control, experimental-1, and experimental-2 groups were treated with non-resorbable membranes only, autogenous tooth bone grafts with non-resorbable membranes, and autogenous tooth bone grafts with resorbable membranes, respectively. Healing patterns were observed 4 to 8 weeks after treatment. Mesio-distal sections were obtained and stained with hematoxylin and eosin, and histological and histomorphometrical analyses were performed. Four weeks after treatment, connective tissue and autogenous tooth bone graft materials with newly formed bone were observed. Partial recovery of periodontal ligament-like tissue and formation of cementum-like tissue at root surfaces also occurred. Eight weeks after treatment, mature bone tissue formation was noted. In addition, regular thickness of cementum-like tissue at root surfaces, and improved periodontal ligament-like tissue were observed. Areas of newly formed tissue were 92.2% ± 13.0%, 97.4% ± 4.4%, and 98.1% ± 2.8% at 4 weeks after treatment, and 96.7% ± 3.7%, 96.8% ± 5.7%, and 99.6% ± 0.8% by 8 weeks post-treatment, in the control, experimental-1, and experimental-2 groups, respectively. Regeneration of defective tissues occurred in the experimental group compared with the control group, but not significantly. This study showed that combining autogenous tooth bone grafts with membranes in class II furcation defects improves healing efficiency.
키워드
Bone substitutes; Furcation defects; Guided tissue regeneration
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